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Original Article
Significance of Polymerase Chain Reaction Test for Diagnosis of Mycoplasma pneumoniae Pneumonia
Hae-kyung Lim, Young-Hun Chung
Clin Exp Pediatr. 1999;42(2):173-179.   Published online February 15, 1999
Purpose : Mycoplasma pneumoniae is a common cause of lower respiratory disease, especially in children and young adults. The diagnosis, in most cases, is confirmed by serology. M. pneumoniae is difficult to culture because of its fastidious nature, and growth is too slow for diagnostic use. In this prospective study, the sensitivity and specificity of the PCR assay was evaluated...
Relationship between Chest Radiography and Cell-mediated Immunity in Mycoplasma pneumoniae Pneumonia
Yong Dae Ham, Jae Il Yoo, Jin Hwa Jeong, Jeong Ho Lee, Jong Dae Cho
Clin Exp Pediatr. 1998;41(11):1509-1516.   Published online November 15, 1998
Purpose : Mycoplasma pneumoniae pneumonias have been one of the most common causes of lower respiratory tract diseases during childhood. It is suggested that pathologic changes seen in the lung tissues were the histologic expression of the host immune response. The aim of this study was to determine the relationship between the chest radiographic pattern of Mycoplasma pneumoniae pneumonia and...
The Diagnostic Value of Polymerase Chain Reaction in Mycoplasma pneumoniae Pneumonia
Han Wook Kang, Byung Moon Ahn, Moo Young Song, Eun Ryoung Kim, Suk Ho Choi, Il Soo Kim
Clin Exp Pediatr. 1998;41(10):1351-1358.   Published online October 15, 1998
Purpose : This study was performed to evaluate the polymerase chain reaction(PCR) in the diagnosis of Mycoplasma pneumoniae pneumonia in comparison with the specific antibody test. Methods : Five hundred and ten patients with pneumonia, ranging from the ages of 8 months to 15 years who were admitted in Sung-Ae and Kwangmyung Sung-Ae general hospitals from Nov. 1996 to Oct....
Study of Seroprevalence of Antimycoplasma Antibody in Healthy Children and its Diagnostic Value
Soo Kyung Choi, Ji Ah Jung, Kyung Hyo Kim, Gyoung Hee Kim
Clin Exp Pediatr. 1998;41(4):489-497.   Published online April 15, 1998
Purpose : To evaluate the diagnostic reliability of the single serum titers of the specific serum antibody determiantion method, we compared antimycoplasma antibody titers of 177 healthy children with 353 children who had respiratory symptoms indicative of Mycoplasma pneumoniae infection. Methods : We used Serodia-Myco II particle agglutination test and the titers of ≥1:40 were regarded as positive. Results : Age distribution of 177 healthy...
Clinical Change of Mycoplasma Pneumonia
Jae Bum Lee, Kyong Tae Whang, Jeong Hyun Kim, Kyong Og Ko, Ji Hee Cho, Yun Duk Yoo
Clin Exp Pediatr. 1998;41(3):315-322.   Published online March 15, 1998
Purpose : It was noted some changes of clinical manifestations of mycoplasma pneumonia. we reviewed and compared these changes and saught any clues causes for proper dignosis and treatment. Methods : We divided patients with mycoplasma pneumonia into two groups, Group 1(from Jan. to Dec. 1996) and Group 2(from Jan. to Dec. 1994), and analyzed clinical, radiologic, and serologic differences. Results :...
Efficacy of Mycoplasma Antibody Test and Cold Agglutinin Test in the Diagnosis of Mycoplasma Pneumonia in Children
Jung Ae Son, Weon Par, Dong Jin Lee
Clin Exp Pediatr. 1998;41(2):179-185.   Published online February 15, 1998
Purpose : This study was done to compare the diagnostic value of the Mycoplasma antibody (M- Ab) test and the cold agglutinin(CA) test from the onset of Mycoplasma pneumoniae pneumonia to its diagnosis in children. Methods : We analyzed 48 cases of M. pneumoniae pneumonia in children who were admitted to the Pediatric Department of Ulsan Dongkang General Hospital for 1...
Case Report
A Case of Lipoid Pneumonia with Hypercalcemia Caused by SqualelneⓇ Intake by Force
Young Kyoun Kim, Ho Suk Kang, Seung Cheol Lee, Chong Guk Lee, Sang Woo Kim
Clin Exp Pediatr. 1997;40(12):1745-1749.   Published online December 15, 1997
Lipoid pneumonia is a chronic, interstitial, proliferative inflammation resulting from aspiration of lipoid material and occurs principally in debilated infants. We experienced a case of lipoid pneumonia with hypercalcemia in a 15 month-old boy who showed irritability, poor weight gain, cough, dyspnea, fatigue, diarrhea and pale face after ingestion of SqualeneⓇ(shark liver oil : 20-30 cap/day) by force for 2 months. Calcium preparation was also...
Original Article
Rapid Identification of Mycoplasma Pneumoniae, Mycobacterium Tuberculosis and Staphylococcus Aureus in Pleural Fluid by PCR
Chang Wan Kim, Byung Moon Ahn, Eun Ryoung Kim, Il Su Kim, Yung Seuk Pak, Sang Chul Sung
Clin Exp Pediatr. 1997;40(9):1232-1241.   Published online September 15, 1997
Purpose : Pleural effusions may develop during the course of bacterial pneumonia. The aim of this study was to evaluate the significance of the polymerase chain reaction(PCR) method for detection of M ycoplasma pneumoniae, M ycobaterium tuberculosis and Staphylococcus aureus from pleural fluid. Methods : Total 12 samples were obtained from pleural fluid; 2 samples from children with Mycoplasma pneumonia, 5 samples from adults with...
Occurrence of Mycoplasma pneumoniae Pneumonia in Seoul, Korea, from 1986 to 1995
Jung-Yun Hong, Song-Yi Nah, Seung-Gon Nam, Eun-Hwa Choi, Jin-Young Park, Hoan-Jong Lee
Clin Exp Pediatr. 1997;40(5):607-613.   Published online May 15, 1997
Case Report
A Case of Lymphocytic Interstitial Pneumonia
Ho Young Lee, Hwang Min Kim, Mee Kyung Namgoong, Jong Soo Kim, Soon Hee Jung, Dong Jin Kim
Clin Exp Pediatr. 1997;40(4):572-577.   Published online April 15, 1997
Lymphoid interstitial pneumonia(LIP) is an uncommon process in childhood, and is characterized by interstitial accumulation of mature lymphocytes, plasma cells and reticuloendothelial cells. LIP is believed to have autoimmune or immunologic pathogenesis, because it is frequently associated with acquired immune deficiency syndrome, Epstein-Barr virus infection, common variable immunodeficiency. The patient described in this report had idiopathic thrombocytopenic purpura, Evans syndrome...
A Case of Tuberculous Pneumonia in Infancy
Joon-Sung Lee, Young-Yoo Kim, Jong-Wan Kim
Clin Exp Pediatr. 1997;40(4):559-566.   Published online April 15, 1997
A rare but serious complication of tuberculosis in a child occurs when the primary infection is progressively destructive. It is difiicult to differentiate from other bacterial pneumonias. We experienced a case of tuberculous pneumonia in a 73-days-old male who presented with cough, fever and progressive dyspnea. Chest X-ray shows diffuse pneumonic consolidation on right upper lung field, Mantoux test was positive...
Original Article
Relationship between Complications of Mycoplasma Pneumonia and Titers of Cold Agglutinin and Mycoplasma Antibody in Children
Sung Soo Rim, Myung Hyun Cho, Byung Min Moon, Kyoung Sim Kim, Kibok Kim
Clin Exp Pediatr. 1996;39(12):1680-1689.   Published online December 15, 1996
Purpose : To assess the relationship between the complications of mycoplasma pneumonia and titers of cold agglutinin and mycoplasma antibody in children. Methods : 120 cases of mycoplasmal pneumonia in children who were admitted to the Pediatric Department of Kwangju Christian Hospital between June 1993 and May 1994 were analyzed. Results : 1) The peak incidence of age was between 2 and...
Ten Cases of Severe Adenoviral Pneumonia in the Spring 1995
Jeong Hee Kim, Sang Il Lee, Mun Hyang Lee, I Seok Kang, Heung Jae Lee, Bo Kyung Kim, Yeon-Lim Suh
Clin Exp Pediatr. 1996;39(9):1247-1253.   Published online September 15, 1996
Purpose : In the Spring 1995, there was an outbreak of adenoviral infection, which caused four death out of ten patients with adenoviral pneumonia in our hospital. Clinical courses of ten patients with severe pneumonia were similar each other, and two were confirmed as adenoviral pneumonia by postmortem autopsy. Although not proven, we believe eight patients had adenoviral pneumonia. Therefore, we report clinical features...
Cold Agglutinin and Mycoplasma Antibody Titersin Children with Mycoplasma pneumoniae Pneumonia During Recent 5 Years
Seon Hwa Yoon, Joon Kyo Jung, Myung Ho Oh
Clin Exp Pediatr. 1996;39(7):943-952.   Published online July 15, 1996
Purpose : More effective diagnosis and treatment through a survey on clinical aspect for the last 5 years and interrelation between cold agglutinin titer and mycoplasma antibody titer of Mycoplasma pneumoniae pneumonia. Methods : 369 patients hospitalized in the department of pediatrics of Chung Goo Sung Shim Hospital for the 5 years from January 1990 to December 1994 have been surveyed, which diagnosed to be...
Neurologic Complications Associated with Mycoplasma pneumoniae Infection
Sung-Jong Park, Tae-Sung Ko, Hyung-Nam Moon, Chang-Yee Hong
Clin Exp Pediatr. 1996;39(3):346-353.   Published online March 15, 1996
Purpose : Mycoplasma pneumoniae is known to be a common respiratory pathogen in children and cause neurologic complications in some patients. The clinical spectrum of the neurologic complications is wide, ranging from mild meningeal signs to severe neurologic symptoms with poor outcomes. The overall mortality in patients with neurologic complications has been approximated upto 10% and significant residual deficits could...
Case Report
A Case of Cerebral Infarction Associated with Mycoplasma pneumoniae Infection
Young Jae Koh, Dong Jun Kim, In Joon Seol, Ha Baik Lee, Ki Woong Hong
Clin Exp Pediatr. 1996;39(1):115-119.   Published online January 15, 1996
Mycoplasma pneumoniae has been shown to be of etiologic importance in cases of upper-and lower-respiratory tract infections, especially in children and young adults. It may cause a variety of extrapulmonary manifestations in multiple organ systems, most commonly the central nervous system. The extrapulmonary syndromes include meningitis, cerebral infarction, acute transverse myelitis, psychosis, cerebellar ataxia, Guillain-Barré syndrome and Reye syndrome. Cerebral...
A Case of Newborn Sepsis Caused by Streptococcus pneumoniae
Eun Ha Choi, Seong Hee Jang, Eun Sil Dong, Young Min Ann
Clin Exp Pediatr. 1995;38(12):1690-1693.   Published online December 15, 1995
Systemic infection due to Streptococcus pneumoniae is a serious, albeit rare disease in the neonatal period. There is no case of pneumococcal sepsis reported in Korea. The results of epidemiologic studies suggest that the majority of infants with pneumococcal septicemia acquire the microorganisms either by the ascending route or during passage throught the birth canal. The mortality is high in...
Original Article
A Study of Relationship between Bronchial Hyperreactivity (BHR) and Atopic Findings in Mycoplasma pneumoniae Pneumonia
In Kyeong Seo, Weon Jeong Bae, Jae Ook Lee, Im Ju Kang
Clin Exp Pediatr. 1995;38(9):1210-1219.   Published online September 15, 1995
Purpose : The respiratory infection due to Mycoplasma pneumoniae among school aged children and adolescents was recognized as an important cause of wheezing or BHR. This study was performed to evaluate relationship between BHR to Mch inhalation challenge and atopic findings in M. pneumoniae pneumonia. Methods : 61 patients with M. pneumoniae pneumonia who were admitted to the department of Pediatrics,...
Detection of Mycoplasma pneumoniae in clinical Samples from Pediatric Patients by Polymerase Chain Reaction
Baik-Lin Eun, Sang Hee Park, Young Chang Dockgo, Sang Chul Seong
Clin Exp Pediatr. 1995;38(8):1077-1086.   Published online August 15, 1995
Purpose : Mycoplasma pneumoniae is a common cause of a wide rage of upper and lower respiratory tract infections, especially in children and young adults. Routine laboratory diagnosis of M.pneumoniae infection is based mainly on serology and, to lesser extent, on cultivation. The cultivation of M.pneumoniae, a fastidious microorganism, is time-consuming and may require 1-3 weeks for results. Serological procedures...
Case Report
One Case of Bronchiolitis Obliterans Associated with Stevens-Johnson Syndrome due to Mycoplasma pneumoniae In fection
Soo Kyung Lee, Joon Soo Lee, Soo Young Lee, Byung Ju Jeoung, Kyu Earn Kim, Ki Young Lee
Clin Exp Pediatr. 1993;36(10):1441-1446.   Published online October 15, 1993
Bronchiolitis obliterans is an infrequent disorder characterized by partial or complete obstruction of bronchi and bronchioles by fibrous tissue following an insult to the lower respiratory tract. In the pediatric population, Bronchiolitis obliterans has most frequently been preceded by respiratory tract infection by adenovirus, influenza, measles. But it may occur in young adults after mycoplasma infection. We experienced the case...
Original Article
A Clinical Study on Wheezing of Mycoplasma Pneumoniae Pneumonia in Children
Jeong Eun Kwon, Jun Ho Yoon, Jae Ook Lee, Im Ju Kang
Clin Exp Pediatr. 1993;36(10):1366-1374.   Published online October 15, 1993
The relationship between respiratory infections and exacerbations of wheezing in patients with wheezy bronchitis or asthma has been described. Most respiratory infections were viral or Mycoplasma pneumoniae. This study was performed to evaluate the effect of Mycoplasma pneumoniae infection on bronchial reactivity and atopic background. 106 patients with Mycoplasma pneumoniae pneumonia who were admitted to the department of pediatrics, Fatima Hospital,...
Clinical Consideration between the Type of pneumonia and cold Agglutinin Titer, and Mycoplasma Antibody Titer caused by Mycoplasma pneumonia in Children
Byung Yeon Kim, Hyang Suk Lee, Ill Kyung Kim, Chang Hee Choi, Jyung Ho You
Clin Exp Pediatr. 1993;36(7):959-967.   Published online July 15, 1993
The authors analysed 261 cases of mycoplasmal pneumonia in chidren who were admitted to the pediatric department of Seoul Adventist Hospital between July 1986 and June 1991. The result obtained were as follows; 1) Yearly distribution of the cases showed high in 1987 and 1991, but no significant difference was noted in seasonally or monthly distribution. 2) The peak incidence of age was...
Clinical and Epidemiologic Features of Respiratory Syncytial Virus Infection
Hoan Jong Lee, Seong Hee Jang
Clin Exp Pediatr. 1992;35(10):1389-1401.   Published online October 15, 1992
Although lower respiratory tract infection is a major cause of childhood morbidity in Korea and respiratory viruses are presumed to be important pathogens, there have been few studies available. We diagnosed RSV infection by virus isolation and immunofluorescence in children with lower respiratory tract infection, seen at Seoul National University Children's Hospital from Nov. 1990 to Jul. 1991. The results were...
A Clinical Study of Mycoplasma Pneumonia in Children During Recent 5 Years
In Seung Park, Ha Baik Lee
Clin Exp Pediatr. 1992;35(8):1082-1088.   Published online August 15, 1992
Mycoplasma pneumoniae infections are among the most frequent respiratory diseases of school-aged children, adolescents and young adults. However in preschool children a persistent nonproductive cough, fever and interstitial or lobular infiltrates on the chest radiograph can recently be recognized as presenting features of M. pneumoniae. We studied to find out the recent trends in epidermiologic and clinical variabilities of M. pneumoniae...
Cytomegalovirus Infection in Children: The Significance of CMV Specific IgM Antibody Test and Virus Isolation in the Urine
Dong Wook Kim, Hyun Kwack, Seong Hee Jang, I Seok Kang, Hoan Jong Lee, Jung-Hwan Choi, Jeong Kee Seo, Chong Ku Yun
Clin Exp Pediatr. 1992;35(7):890-901.   Published online July 15, 1992
The clinical pictures of 44 children with IgM antibody to CMV (cytomegalovirus) by ELISA(enzyme linked immunosorbent assay) were reviewed retrospectively, and the significance of serum CMV specific IgM antibody and virus isolation in the urine was analyzed. Age of the patients with IgM antibody to CMV ranged from 23 days to 8 years 7 months, and median age was 2 months....
Case Report
A Case of Chronic Recurrent Obstructive Bronchitis Associated with Gastro-Esophageal Reflux
Myung Hee Min, Sang Soo Roh, Sang Il Lee, Sang Woo Kim
Clin Exp Pediatr. 1992;35(4):556-562.   Published online April 15, 1992
It has been well established that the gastroesophageal reflux and chronic respiratory problem were closely related. Several reports in pediatric literature have implicated the aspiration of gasrtric contents as a trigger factor of cough, wheezing, and recurrent pulmonary disease. Several possible mechanisms have been proposed whereby acidic gastric content can trigger bronchospasm and, in turn, bronchospams can trigger gastroesopohageal reflux. Several tests,...
Original Article
Clinical Study of Mycoplasmal Pneumonia Syndrome in Children
Hyeon-Hi Kim, Hung-Ki Min, Seung-Hoon Han, Jin-Han Kang, Joon-Sung Lee, Sung-Hoon Cho
Clin Exp Pediatr. 1992;35(4):451-458.   Published online April 15, 1992
Between September 1, 1989 and August 31, 1990, we studied 142 cases of mycoplasmal p neumonia syndrome in children who were admitted to the pediatric department of Catholic University Medical College. The results were as follows; 1) The highest incidence was in the age of 6 years in 27 cases and the male to female ratio...
The diagnosis of mycoplasma pneumoniae pneumonia by high density composite particles agglutinin test.
Hae Jin Choeh, Jung Hae Park, Chong Sung Chung, Kyu Chul Choeh
Clin Exp Pediatr. 1991;34(8):1102-1109.   Published online August 31, 1991
In a prospective investigation of 21 chi Idem 3 years of age or more with Mycoplasma pneumoniae pneumonia, we analyzed the diagnostic efficacy of High Density Composite Particles Agglutinin(HDDA) test comparing with cold agglutinin tests and clinical findings. The results obtained were as followed. 1) Among 24 total cases, the number of cases showing positive reaction to HDPA and to cold agglutination test were 17 and...
A clinical study of pneumonia presented with positive cold agglutin- in test.
Il Jung Joo, Jin Seop Juong, Sang Woo Kim
Clin Exp Pediatr. 1991;34(8):1093-1101.   Published online August 31, 1991
A clinical study was performed on 65 patients with Mycoplasma pneumoniae pneumonia who were admitted to the Department of Pediatrics of Seoul Paik hospital from September 1,1989 to August 31, 1990. The results were as follows; 1) Seasonal distribution showed a high frequency in summer (33 cases; 50.8%). 2) The peak incidence was 5 to 9 years of age (32cases;49.2%). 3) Male to female ratio was 1:1.17(30:35). 4) On the chest...
Clinical study on lipoid pneumonia caused by aspiration of squalene.
Dong Joo Shin, Beom Soo Park, Moon Sun Yang, Heon Seok Han, Young Yull Koh, Hyung Ro Moon, Chang Yeon Lee
Clin Exp Pediatr. 1991;34(5):654-661.   Published online May 31, 1991
A clinical observation was made on 14 cases of lipoid pneumonia, who visited department of pediatrics, Seoul National University Children’s Hospital from August, 1988 to June, 1990. The results were as follows; The ratio of male to female was 10 : 4. Age at diagnosis was 1.1±1. 3 years, and ranged from 3 months to 4.9 years. The age at taking Squalene ranged...
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